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The Hidden Heroes in Your DNA: Retrocopies and Their Role in Fighting Viruses
Research from PNRI’s McLaughlin Lab has found that our genomes harbor retrocopies of a specific family of genes called APOBEC3, which play a crucial role in restricting viral infections. What’s more, these retrocopies are capable of fighting off viruses when tested in the lab.
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Bold Breakthroughs: PNRI’s Night of Celebration, Science, and Hope
In late October, PNRI celebrated recent achievements and ongoing innovation in the field of genetic research with our event: Bold Breakthroughs, an enthusiastic return to in-person events for the institute after a four-year hiatus from our classic annual fundraiser, Evening of Wine. Bold Breakthroughs represented a fresh and energizing adaptation of that classic and was…
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Unlocking the Secrets of Complex Genomic Rearrangements in Disease
In a pair of recent studies, PNRI’s Carvalho Lab is making significant strides in unraveling the intricate relationship between our genes and their structure, shedding new light on the genetic underpinnings of specific diseases.
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The New York Times Covers PNRI’s Breakthrough Research on Ancient Cancer in Clams
The New York Times featured Dr. Michael Metzger’s groundbreaking research on transmissible cancer in clams in: Bizarre Cancer Has Been Spreading Among Shellfish for Centuries, Studies Find.
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Genomic Analysis Reveals Ancient Cancer Lineages in Clams
In a new study published in the journal Nature Cancer, Michael Metzger, Ph.D., Assistant Investigator at Pacific Northwest Research Institute (PNRI), and a global team of co-investigators have conducted a comprehensive analysis of the genomic changes associated with a unique cancer in clams. The cancer is “transmissible” in that the cancer cells themselves jump from…
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Expanding Newborn Screening Panels in the Genomic Era
The pace of genetic discovery has expanded the ability to diagnose more of the rare, inherited diseases that threaten the lives of newborns. And yet, the pace of adding new diseases to the newborn screening program is lagging.
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Mentoring Tomorrow’s Genetic Innovators
The Summer Undergraduate Research Internship (SURI) is integral in PNRI, where scientists value mentoring the next generation. This summer we proudly hosted five exceptional interns with diverse interests and career goals as they got hands-on training in our laboratories.
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Washington Research Foundation awards $100,000 to Pacific Northwest Research Institute in honor of David J. Galas, Ph.D.
Washington Research Foundation awards $100,000 to Pacific Northwest Research Institute in honor of David J. Galas, Ph.D. The funding will support continuation of work started by Galas and Lisa Stubbs, Ph.D. to identify genetic factors influencing brain’s response to stress.
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Save the Date for Bold Breakthroughs
PNRI is excited to host our annual event this fall! Join PNRI for Bold Breakthroughs: a night of thrilling discovery and fine wine on Friday, October 20, 2023. We invite you to an evening that brings cutting-edge genetics research from our labs to the beautiful AXIS venue in Pioneer Square. “We are so excited to…
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Decoding the Genetics of Stress
In the not-so-distant past, a typical doctor’s visit for many of us might have focused on problematic symptoms or an ongoing physical health issue. We didn’t expect to discuss social stressors like demanding jobs, family obligations, financial hardships, or the recent death of a loved one.