PNRI’s Science Matters free, virtual seminars feature discussions with scientists around the globe about exciting research in genetics, genomics, and evolutionary biology with important societal impact.
Topics include research on the genetics of ethnically diverse populations, diseases afflicting vulnerable or underserved groups, and efforts to expand the diversity (broadly defined) of research subjects or the scientific workforce.
The seminars are free to attend and open to the scientific community and anyone interested in learning more about genetics. These are virtual events (via Zoom) and require advance registration. Each seminar has a unique registration link. Register for our next seminar at the bottom of this page.
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12:00 – 1:15 pm (PDT)
Principal Investigator, Ray Lab, Center for Systems Immunology, Benaroya Research Institute
You Can’t See the Trees for the Forest: Dissecting the Many Causal Roots Driving Autoimmune Disease Genetic Risk
Dr. Ray will discuss how genetic risk for autoimmune diseases is driven mostly by genetic variation that falls within cryptic non-coding regions. To dissect the hundreds of genetic risk mechanisms that drive these diseases, the Ray Lab employed high throughput perturbational methods that evaluate autoimmune variant effects on gene expression and cellular function in primary human T cells.