PNRI has five distinguished scientists leading laboratories. Each of our investigators explores a different aspect of the interplay between genetics and the environment to understand our resilience or susceptibility to a wide variety of diseases. What unites them is a passion for scientific research that will ultimately improve human health.
Cláudia Carvalho, PhD
The Carvalho Lab investigates the molecular causes of rare genetic diseases, such as primary immunodeficiency and Robinow Syndrome, and their impact on human health and development.
Aimée Dudley, PhD
The Dudley Lab focuses on improving methods for genetic mapping, using high throughput assays to assess the functional impact of variation in the human genome, and circumventing antifungal drug resistance.
Rick McLaughlin, PhD
The McLaughlin Lab studies transposable elements to improve our understanding of the biological underpinnings of autoimmune diseases and how hidden variation in transposable element-created sequence can alter an individual’s susceptibility to disease.
Michael Metzger, PhD
The Metzger Lab investigates rare contagious cancers in bivalves to understand how cancers evolve and to use that information to learn new ways to block cancer in humans.
Lisa Stubbs, PhD
The Stubbs Lab studies the genetics of brain development, and how differences in brain development translate into individual behaviors and susceptibility/resilience to disease.
David Galas, PhD
The Galas Lab develops new methods and tools for the analysis of biological data. These information theory-based methods enable some novel genetic analysis, including the detection of modifier genes.