Creative thinking to power medical breakthroughs

PNRI scientists unravel the powerful mysteries of the human genome through the lens of “what keeps us healthy” to drive future medical innovations.

Scientific discoveries found in unexpected places

From contagious cancer in clams to rare inherited metabolic disorders to junk DNA—PNRI labs delve into unexplored areas to uncover the next scientific breakthrough.

Invest in boundary-breaking science

Invest in PNRI’s bold approach to tackling the most difficult questions in science and medicine. Together, we are improving human health for generations to come.

Boundless Exploration

PNRI’s relentless pursuit of scientific discovery is fueled by our intrinsic ambition to create a healthier future for all humans.

Delve into PNRI Labs

Unlocking Insights From Transmissible Cancers in Nature

Explore the Metzger Lab’s work to uncover how clams and other bivalves have developed resistance to rare transmissible cancers – and how these findings may lead to new ways to block cancer in humans.

rare disease

Solving the Unsolved Cases of Rare Diseases

Learn how the Carvalho Lab dives deep into the human genome to identify DNA structural variants linked to rare diseases like Robinow Syndrome and MECP2 duplication syndrome. Their innovative tools pinpoint these genetic structures, advancing diagnosis and treatment for rare diseases.

Culture of Intellectual Freedom

“PNRI is a creative, invested, and non-traditional institute that is pursuing a daring style of science.” – Dr. Rick McLaughlin, PNRI Assistant Investigator 

Latest News

  • Solving the Unsolved Cases of Rare Diseases

    Dr. Cláudia Carvalho and her team at PNRI are on a mission to diagnose rare diseases that have long baffled the medical community. With a focus on genetic structural variants, often undetected in standard tests, their work is pushing the boundaries of what’s possible in genetics.

  • Michael Metzger featured in Discovery Series!

    PNRI’s Dr. Michael Metzger kicks off Tech Alliance’s 2024-25 Discovery Series on Friday, September 13th at Slalom Hawk Tower. Join us for this presentation!

  • Changing the Tide of Cancer With Clams

    Explore Dr. Michael Metzger’s groundbreaking research on contagious cancer in clams, uncovering insights that could revolutionize cancer treatment in humans.

Upcoming Event

PNRI’s Science Matters free, virtual seminars feature discussions with scientists around the globe about exciting research in genetics, genomics, and evolutionary biology with important societal impact. 

December

11

12:00 noon – 1:15 pm PT

Science Matters Seminar

Support bold scientific research at PNRI

Together with our donors, we are improving human health for generations to come.