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The Hidden Heroes in Your DNA: Retrocopies and Their Role in Fighting Viruses
Research from PNRI’s McLaughlin Lab has found that our genomes harbor retrocopies of a specific family of genes called APOBEC3, which play a crucial role in restricting viral infections. What’s more, these retrocopies are capable of fighting off viruses when tested in the lab.
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Unlocking the Secrets of Complex Genomic Rearrangements in Disease
In a pair of recent studies, PNRI’s Carvalho Lab is making significant strides in unraveling the intricate relationship between our genes and their structure, shedding new light on the genetic underpinnings of specific diseases.
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The New York Times Covers PNRI’s Breakthrough Research on Ancient Cancer in Clams
The New York Times featured Dr. Michael Metzger’s groundbreaking research on transmissible cancer in clams in: Bizarre Cancer Has Been Spreading Among Shellfish for Centuries, Studies Find.
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Genomic Analysis Reveals Ancient Cancer Lineages in Clams
In a new study published in the journal Nature Cancer, Michael Metzger, Ph.D., Assistant Investigator at Pacific Northwest Research Institute (PNRI), and a global team of co-investigators have conducted a comprehensive analysis of the genomic changes associated with a unique cancer in clams. The cancer is “transmissible” in that the cancer cells themselves jump from…
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Expanding Newborn Screening Panels in the Genomic Era
The pace of genetic discovery has expanded the ability to diagnose more of the rare, inherited diseases that threaten the lives of newborns. And yet, the pace of adding new diseases to the newborn screening program is lagging.
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Mentoring Tomorrow’s Genetic Innovators
The Summer Undergraduate Research Internship (SURI) is integral in PNRI, where scientists value mentoring the next generation. This summer we proudly hosted five exceptional interns with diverse interests and career goals as they got hands-on training in our laboratories.
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DNA Today Podcast Explores Three Perspectives on Dudley Lab’s Research Revolutionizing Diagnosis and Treatment of OTC Deficiency
PNRI’s Dr. Aimée Dudley joins Dr. Andrea Gropman of Children’s National Hospital and Tresa Warner of the National Urea Cycle Disorders Foundation to discuss a novel genetic screening tool that offers hope to babies born with OTC deficiency, a life-threatening metabolic disorder.
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PNRI Welcomes Shirin McConaghy to Board of Trustees
Today, we warmly welcome Shirin McConaghy to PNRI’s esteemed Board of Trustees.
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Media Roundup: PNRI’s Metzger Lab Investigates Contagious Cancer in Shellfish
PNRI’s Metzger Lab and collaborators from across the globe recently launched a study investigating how a virus-like cancer spreads among basket cockles on the Pacific Coast and soft-shell clams on the Atlantic Coast.
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PNRI Mourns the Loss of David J. Galas, PhD
Pacific Northwest Research Institute (PNRI) mourns the loss of David J. Galas, PhD who passed away on May 27, 2023, after a hard-fought battle with cancer. Dr. Galas was a world-renowned expert in molecular biology and genetics whose long and distinguished career led to contributions in the fields of physics, mathematics, and biology. While his…
