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April 26, 2025 | bioRxiv
Metzger Lab

Variation in Natural Infection Outcomes and Cancer Cell Release from Soft-Shell Clams (Mya arenaria) with Bivalve Transmissible Neoplasia

Rachael M. Giersch, Jordana K. Sevigny, Sydney A. Weinandt, Carissa Mayo, Fiona E. S. Garrett, Karyn Tindbaek, Marisa A. Yonemitsu, Samuel F. M. Hart, Michael J. Metzger

March 31, 2025 | PLoS Genetics
Metzger Lab

Gene expression in soft-shell clam (Mya arenaria) transmissible cancer reveals survival mechanisms during host infection and seawater transfer

Samuel F.M. Hart, Fiona E. S. Garrett, Jesse S. Kerr, Michael J. Metzger

February 20, 2025 | Molecular Ecology
Metzger Lab

Multiple lineages of transmissible neoplasia in the basket cockle (Clinocardium nuttallii) with repeated horizontal transfer of mitochondrial DNA

Marisa A. Yonemitsu, Jordana K. Sevigny, Lauren E. Vandepas, James L. Dimond, Rachael M. Giersch, Helen J. Gurney-Smith, Cathryn L. Abbott, Janine Supernault, Ruth Withler, Peter D. Smith, Sydney A. Weinandt, Fiona E. S. Garrett, Robin Little Wing Sigo, Elizabeth Unsell, Ryan N. Crim, Michael J. Metzger

January 1, 2025 | Cancer Discovery
Metzger Lab

Peto’s Paradox Is Dead. Long Live Peto’s Paradox

Michael J. Metzger

December 7, 2024 | bioRxiv
Metzger Lab

Identification of an Outbreak of Bivalve Transmissible Neoplasia in Soft-Shell Clams (Mya arenaria) in the Puget Sound Using Hemolymph and eDNA Surveys

Sydney A. Weinandt, Zachary J. Child, Dorothy Lartey, Angel Santos, Holden Maxfield, Jordana K. Sevigny, Fiona E. S. Garrett, Peter D. Smith, Rachael M. Giersch, Samuel F. M. Hart, Franchesca Perez, Lucas Rabins, Samuel Kaiser, Anna Boyar, Jan Newton, Jesse Kerr, James L. Dimond, Michael J. Metzger

July 31, 2024 | Journal of Shellfish Research
Metzger Lab

Application of Hemolymph Smear Histology Diagnosis to Detect Disseminated Neoplasia in Basket Cockles (Clinocardium nuttallii)

Lauren E Vandepas, Ryan N Crim, Emily Gilbertson, Marisa A Yonemitsu, Elizabeth Unsell, Michael J Metzger, Adam Lacy-Hulbert, Frederick W Goetz

April 26, 2024 | Biological Research
Metzger Lab

Identification and expression analysis of two steamer-like retrotransposons in the Chilean blue mussel (Mytilus chilensis)

Gloria Arriagada, Johan Quezada, Nicolas Merino-Veliz, Fernando Avilés, Diana Tapia-Cammas, Jorge Gomez, Daniela Curotto, Juan A Valdes, Pablo A Oyarzún, Cristian Gallardo-Escárate, Michael J Metzger, Marco Alvarez

October 2, 2023 | Nature Cancer
Metzger Lab

Centuries of genome instability and evolution in soft-shell clam, Mya arenaria, bivalve transmissible neoplasia

Samuel F. M. Hart, Marisa A. Yonemitsu, Rachael M. Giersch, Fiona E. S. Garrett, Brian F. Beal, Gloria Arriagada, Brian W. Davis, Elaine A. Ostrander, Stephen P. Goff & Michael J. Metzger

June 29, 2023 | bioRxiv
Metzger Lab

A rapid, inexpensive, non-lethal method for detecting disseminated neoplasia in a bivalve

Lauren E Vandepas, Ryan N Crim, Emily Gilbertson, Marisa A Yonemitsu, Elizabeth Unsell, Michael J Metzger, Adam Lacy-Hulbert, Frederick W Goetz

August 11, 2022 | bioRxiv prepint.
Metzger Lab

Centuries of genome instability and evolution in soft-shell clam transmissible cancer

Samuel F.M. Hart, Marisa A. Yonemitsu, Rachael M. Giersch, Brian F. Beal, Gloria Arriagada, Brian W. Davis, Elaine A. Ostrander, Stephen P. Goff, Michael J. Metzger