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December 1, 2022 | Pediatric Diabetes
Hagopian Lab

HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children

Salami F, Tamura R, You L, Lernmark Å, Larsson HE, Lundgren M, Krischer J, Ziegler AG, Toppari J, Veijola R, Rewers M, Haller MJ, Hagopian W, Akolkar B, Törn C; TEDDY Study Group

December 1, 2022 | Diabetes
Hagopian Lab

Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals With Presymptomatic Type 1 Diabetes

Kwon BC, Achenbach P, Anand V, Frohnert BI, Hagopian W, Hu J, Koski E, Lernmark Å, Lou O, Martin F, Ng K, Toppari J, Veijola R

October 1, 2022 | Diabetes Care
Hagopian Lab

Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes: The TEDDY Study

Krischer JP, Liu X, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B; TEDDY Study Group

October 1, 2022 | Diabetes Care
Hagopian Lab

Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests

Vehik K, Boulware D, Killian M, Rewers M, McIndoe R, Toppari J, Lernmark Å, Akolkar B, Ziegler AG, Rodriguez H, Schatz DA, Krischer JP, Hagopian W; TEDDY Study Group

August 4, 2022 | American Journal of Clinical Nutrition
Hagopian Lab

Sources of dietary gluten in the first 2 years of life and associations with celiac disease autoimmunity and celiac disease in Swedish genetically predisposed children: The Environmental Determinants of Diabetes in the Young (TEDDY) study

Hård Af Segerstad EM, Liu X, Uusitalo U, Agardh D, Andrén Aronsson C; TEDDY Study Group

July 5, 2022 | Lancet Diabetes Endocrinol.
Hagopian Lab

Two-age islet-autoantibody screening for childhood type 1 diabetes: a prospective cohort study

Mohamed Ghalwash, Jessica L Dunne, Markus Lundgren, Marian Rewers, Anette-G Ziegler, Vibha Anand, Jorma Toppari, Riitta Veijola, William Hagopian; Type 1 Diabetes Intelligence Study Group

July 1, 2022 | Diabetologia
Hagopian Lab

Congenital beta cell defects are not associated with markers of islet autoimmunity, even in the context of high genetic risk for type 1 diabetes

Wyatt RC, Hagopian WA, Roep BO, Patel KA, Resnick B, Dobbs R, Hudson M; EXE-T1D Consortium; De Franco E, Ellard S, Flanagan SE, Hattersley AT, Oram RA, Johnson MB

June 17, 2022 | Lancet Diabetes Endocrinol.
Hagopian Lab

Type 1 diabetes in diverse ancestries and the use of genetic risk scores

Redondo MJ, Gignoux CR, Dabelea D, Hagopian WA, Onengut-Gumuscu S, Oram RA, Rich SS

June 7, 2022 | Nature Communications
Hagopian Lab

Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study

Auchtung TA, Stewart CJ, Smith DP, Triplett EW, Agardh D, Hagopian WA, Ziegler AG, Rewers MJ, She JX, Toppari J, Lernmark Å, Akolkar B, Krischer JP, Vehik K, Auchtung JM, Ajami NJ, Petrosino JF

May 1, 2022 | Diabetes Care
Hagopian Lab

Utility of Diabetes Type-Specific Genetic Risk Scores for the Classification of Diabetes Type Among Multiethnic Youth

Oram RA, Sharp SA, Pihoker C, Ferrat L, Imperatore G, Williams A, Redondo MJ, Wagenknecht L, Dolan LM, Lawrence JM, Weedon MN, D’Agostino R, Hagopian WA, Divers J, Dabelea D