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Blog

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  • The Hidden Heroes in Your DNA: Retrocopies and Their Role in Fighting Viruses 

    December 2023

    Research from PNRI’s McLaughlin Lab has found that our genomes harbor retrocopies of a specific family of genes called APOBEC3, which play a crucial role in restricting viral infections. What’s more, these retrocopies are capable of fighting off viruses when tested in the lab. 

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  • Bold Breakthroughs: PNRI’s Night of Celebration, Science, and Hope

    November 2023

    In late October, PNRI celebrated recent achievements and ongoing innovation in the field of genetic research with our event: Bold Breakthroughs, an enthusiastic return to in-person events for the institute after a four-year hiatus from our classic annual fundraiser, Evening of Wine. Bold Breakthroughs represented a fresh and energizing adaptation of that classic and was…

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  • DNA

    Unlocking the Secrets of Complex Genomic Rearrangements in Disease

    November 2023

    In a pair of recent studies, PNRI’s Carvalho Lab is making significant strides in unraveling the intricate relationship between our genes and their structure, shedding new light on the genetic underpinnings of specific diseases.

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  • The New York Times Covers PNRI’s Breakthrough Research on Ancient Cancer in Clams

    October 2023

    The New York Times featured Dr. Michael Metzger’s groundbreaking research on transmissible cancer in clams in: Bizarre Cancer Has Been Spreading Among Shellfish for Centuries, Studies Find.

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  • Genomic Analysis Reveals Ancient Cancer Lineages in Clams

    October 2023

    In a new study published in the journal Nature Cancer, Michael Metzger, Ph.D., Assistant Investigator at Pacific Northwest Research Institute (PNRI), and a global team of co-investigators have conducted a comprehensive analysis of the genomic changes associated with a unique cancer in clams. The cancer is “transmissible” in that the cancer cells themselves jump from…

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  • Expanding Newborn Screening Panels in the Genomic Era

    September 2023

    The pace of genetic discovery has expanded the ability to diagnose more of the rare, inherited diseases that threaten the lives of newborns. And yet, the pace of adding new diseases to the newborn screening program is lagging.

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  • Mentoring Tomorrow’s Genetic Innovators 

    September 2023

    The Summer Undergraduate Research Internship (SURI) is integral in PNRI, where scientists value mentoring the next generation. This summer we proudly hosted five exceptional interns with diverse interests and career goals as they got hands-on training in our laboratories.

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  • Washington Research Foundation awards $100,000 to Pacific Northwest Research Institute in honor of David J. Galas, Ph.D.

    August 2023

    Washington Research Foundation awards $100,000 to Pacific Northwest Research Institute in honor of David J. Galas, Ph.D. The funding will support continuation of work started by Galas and Lisa Stubbs, Ph.D. to identify genetic factors influencing brain’s response to stress.

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  • DNA Today Podcast Explores Three Perspectives on Dudley Lab’s Research Revolutionizing Diagnosis and Treatment of OTC Deficiency

    August 2023

    PNRI’s Dr. Aimée Dudley joins Dr. Andrea Gropman of Children’s National  Hospital and Tresa Warner of the National Urea Cycle Disorders Foundation to discuss a novel genetic screening tool that offers hope to babies born with OTC deficiency, a life-threatening metabolic disorder.  

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  • PNRI Welcomes Shirin McConaghy to Board of Trustees

    July 2023

    Today, we warmly welcome Shirin McConaghy to PNRI’s esteemed Board of Trustees.

    Read More
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