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July 3, 2026 | G3 Genes | Genomes | Genetics
Dudley Lab

CYClones: A highly powered, fully genotyped, 8-parent yeast mapping population

Gareth A Cromie, Russell S Lo, Trey S Morgan, Anne E Clark, Julee Ashmead, Martin S Timour, Amy Sirr, Joshua M Akey, Aimée M Dudley

June 17, 2026 | PLoS Genetics
Dudley Lab

Functional profiling of 2,193 ASS1 missense variants: Insights into variant pathogenicity and epistatic interactions in citrullinemia type I

Russell S Lo, Gareth A Cromie, Michelle Tang, Amy Sirr, Ljubica Caldovic, Hiroki Morizono, Nicholas Ah Mew, Andrea Gropman, Aimée M Dudley

May 1, 2026 | Molecular Genetics and Metabolism
Dudley Lab

Two commonly reported incidental OTC variants are associated with late-onset disease

Steven Lang, Russell Lo, Gareth Cromie, Aimée Dudley, Nicholas Ah Mew, Kara Simpson, Vernon R Sutton, Sandra Darilek, Saima Ali, Matthew Snyder, Brendan Lee, Ronit Marom, Sandesh Nagamani, Lindsay Burrage

January 20, 2026 | PNAS
Dudley Lab

Predicting epistasis across proteins by structural logic

Michelle Tang, Gareth A Cromie, Anowarul Kabir, Martin S Timour, Julee Ashmead, Russell S Lo, Nathaniel Corley, Frank DiMaio, Hiroki Morizono, Ljubica Caldovic, Nicholas Ah Mew, Andrea Gropman, Amarda Shehu, Aimée M Dudley

January 15, 2026 | Human Genetics and Genomics Advances
Dudley Lab

Two commonly reported incidental variants in OTC are associated with late-onset disease

Steven H Lang, Russell S Lo, Gareth A Cromie, Aimée M Dudley, Nicholas Ah Mew, Kara Simpson, Vernon Reid Sutton, Sandra Darilek, Saima Ali, Matthew T Snyder, Brendan Lee, Ronit Marom, Sandesh CS Nagamani, Lindsay C Burrage

October 27, 2025 | bioRxiv
Dudley Lab

Pervasive context-dependent effects in the genetic architecture of complex and quantitative traits revealed by a powerful multiparent mapping population in yeast

Gareth A Cromie, Russell S Lo, Lauren Ames, Trey S Morgan, Katherine Owens, Anne E Clark, Martin S Timour, Julee Ashmead, Michelle Tang, J Nathan Kutz, Joshua M Akey, Aimée M Dudley

October 16, 2025 | HGG Advances
Dudley Lab

Two commonly reported incidental variants in OTC are associated with late-onset disease

Steven Lang, Russell Lo, Gareth Cromie, Aimée Dudley, Nicholas Ah Mew, Vernon Sutton, Sandra Darilek, Saima Ali, Matthew Snyder, Brendan Lee, Ronit Marom, Sandesh Nagamani, Lindsay Burrage

September 20, 2025 | bioRxiv
Dudley Lab

Functional Profiling of 2,193 ASS1 Missense Variants: Insights into Variant Pathogenicity and Epistatic Interactions in Citrullinemia Type I

Russell S Lo, Gareth Cromie, Michelle Tang, Amy Sirr, Ljubica Caldovic, Hiroki Morizono, Nicholas Ah Mew, Andrea Gropman, Aimee M Dudley

July 17, 2025 | PLoS Genetics
Dudley Lab

Expectations for papers performing Mendelian randomization analyses

Scott M Williams, Hua Tang, Gregory M Cooper, Anne O’Donnell-Luria, Santhosh Girirajan, Aimée M Dudley, Anne Goriely, Zoltán Kutalik, Xiaofeng Zhu, Giorgio Sirugo, Michael P Epstein

July 1, 2025 | Disease Models & Mechanisms
Dudley Lab

A hypomorphic model of CPS1 deficiency for investigating the effects of hyperammonemia on the developing nervous system

Stuti Bakshi, Taryn Diep, Brandon J Willis, Rachel Reyes, Grace F Wu, Georgios Makris, Martin Poms, Isabel Day, Qin Sun, Irina Zhuravka, Lindsay Lueptow, Michelle Tang, Gareth A Cromie, Aimée M Dudley, Johannes Häberle, Gerald S Lipshutz