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December 5, 2024 | PLOS One
Dudley Lab

Spatiotemporal patterns of gene expression during development of a complex colony morphology

Gareth A Cromie, Zhihao Tan, Michelle Hays, Amy Sirr, Aimée M Dudley

November 28, 2024 | Public Library of Science
Dudley Lab

Onwards! Open science and the (PLOS) genetics community

Dudley AM, Goriely A, Squarr J

April 1, 2024 | Molecular Genetics and Metabolism
Dudley Lab

Poster# 023 Assessing the functional impact of ASL missense variants using high throughput yeast assays

Michelle Tang, Gareth Cromie, Russell Lo, Martin Timour, Hiroki Morizono, Ljubica Caldovic, Nicholas Ah Mew, Andrea Gropman, Aimée Dudley

October 9, 2023 | PLoS Genetics
Dudley Lab

Constructing and interpreting a large-scale variant effect map for an ultrarare disease gene: Comprehensive prediction of the functional impact of PSAT1 genotypes

Michael J. Xie, Gareth A. Cromie, Katherine Owens, Martin S. Timour, Michelle Tang, J. Nathan Kutz, Ayman W. El-Hattab, Richard N. McLaughlin Jr., Aimée M. Dudley

May 4, 2023 | AJHG
Dudley Lab

The functional impact of 1,570 SNP-accessible missense variants in human OTC

Russell S. Lo, Gareth A. Cromie, Michelle Tang, Kevin Teng, Katherine Owens, Amy Sirr, J. Nathan Kutz, Hiroki Morizono, Ljubica Caldovic, Nicholas Ah Mew, Andrew Gropman, Aimée M. Dudley

June 15, 2022 | Yeast
Dudley Lab

A method for quantifying sporulation efficiency and isolating meiotic progeny in non‐GMO strains of Saccharomyces cerevisiae

Amy Sirr, Martin S Timour, Gareth A Cromie, Michelle Tang, Aimée M Dudley

May 17, 2022 | Scientific Data
Dudley Lab

Quantifying yeast colony morphologies with feature engineering from time-lapse photography

Andy Goldschmidt, James Kunert-Graf, Adrian C Scott, Zhihao Tan, Aimée M Dudley, J Nathan Kutz

December 31, 2020 | Frontiers in Genetics
Dudley Lab

Exploiting the autozygome to support previously published mendelian gene-disease associations: An update

Sateesh Maddirevula, Hanan E Shamseldin, Amy Sirr, Lama AlAbdi, Russell S Lo, Nour Ewida, Mashael Al-Qahtani, Mais Hashem, Firdous Abdulwahab, Omar Aboyousef, Namik Kaya, Dorota Monies, May H Salem, Naffaa Al Harbi, Hesham M Aldhalaan, Hamad Alzaidan, Hadeel M Almanea, Abrar K Alsalamah, Fuad Al Mutairi, Samira Ismail, Ghada MH Abdel-Salam, Amal Alhashem, Ali Asery, Eissa Faqeih, Amal AlQassmi, Waleed Al-Hamoudi, Talal Algoufi, Mohammad Shagrani, Aimée M Dudley, Fowzan S Alkuraya

July 1, 2020 | Journal of Inherited Metabolic Disease
Dudley Lab

A yeast‐based complementation assay elucidates the functional impact of 200 missense variants in human PSAT1

Amy Sirr, Russell S Lo, Gareth A Cromie, Adrian C Scott, Julee Ashmead, Mirutse Heyesus, Aimée M Dudley

December 19, 2019 | BMC Molecular and Cell Biology
Dudley Lab

Data-driven multiscale modeling reveals the role of metabolic coupling for the spatio-temporal growth dynamics of yeast colonies

Jukka Intosalmi, Adrian C Scott, Michelle Hays, Nicholas Flann, Olli Yli-Harja, Harri Lähdesmäki, Aimée M Dudley, Alexander Skupin