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May 10, 2021 | BMC Biology
Hagopian Lab

Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo

Holland P, Hagopian WM, Jahren AH, Rusten TE

 

April 1, 2021 | Lancet Diabetes Endocrinol.
Hagopian Lab

Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial

von Herrath M, Bain SC, Bode B, Clausen JO, Coppieters K, Gaysina L, Gumprecht J, Hansen TK, Mathieu C, Morales C, Mosenzon O, Segel S, Tsoukas G, Pieber TR; Anti-IL-21–liraglutide Study Group investigators and contributors

March 31, 2021 | Sci Transl Med.
Hagopian Lab

Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression

Xhonneux LP, Knight O, Lernmark Å, Bonifacio E, Hagopian WA, Rewers MJ, She JX, Toppari J, Parikh H, Smith KGC, Ziegler AG, Akolkar B, Krischer JP, McKinney EF

March 8, 2021 | J Clin Endocrinol Metab.
Hagopian Lab

Factors Associated With the Decline of C-Peptide in a Cohort of Young Children Diagnosed With Type 1 Diabetes

Steck AK, Liu X, Krischer JP, Haller MJ, Veijola R, Lundgren M, Ahmed S, Akolkar B, Toppari J, Hagopian WA, Rewers MJ, Elding Larsson H.

March 1, 2021 | Diabetologia.
Hagopian Lab

First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child’s genetic risk

Johnson SB, Lynch KF, Roth R, Lundgren M, Parikh HM, Akolkar B, Hagopian W, Krischer J, Rewers M, She JX, Toppari J, Ziegler AG, Lernmark Å; TEDDY Study Group

February 24, 2021 | Diabetes Care.
Hagopian Lab

An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood

Bonifacio E, Weiß A, Winkler C, Hippich M, Rewers MJ, Toppari J, Lernmark Å, She JX, Hagopian WA, Krischer JP, Vehik K, Schatz DA, Akolkar B, Ziegler AG; TEDDY Study Group

February 11, 2021 | Sci Rep.
Hagopian Lab

Children’s erythrocyte fatty acids are associated with the risk of islet autoimmunity

Niinistö S, Erlund I, Lee HS, Uusitalo U, Salminen I, Aronsson CA, Parikh HM, Liu X, Hummel S, Toppari J, She JX, Lernmark Å, Ziegler AG, Rewers M, Akolkar B, Krischer JP, Galas D, Das S, Sakhanenko N, Rich SS, Hagopian W, Norris JM, Virtanen SM; TEDDY Study Group

January 25, 2021 | AMIA Annu Symp Proc.
Hagopian Lab

Modeling Disease Progression Trajectories from Longitudinal Observational Data

Kwon BC, Achenbach P, Dunne JL, Hagopian W, Lundgren M, Ng K, Veijola R, Frohnert BI, Anand V; T1DI Study Group

January 1, 2021 | Diabetes.
Hagopian Lab

Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: The TEDDY Study

Li Q, Liu X, Yang J, Erlund I, Lernmark Å, Hagopian W, Rewers M, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP; TEDDY Study Group

December 1, 2020 | Diabetlogia.
Hagopian Lab

Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells

Johnson MB, Patel KA, De Franco E, Hagopian W, Killian M, McDonald TJ, Tree TIM, Domingo-Vila C, Hudson M, Hammersley S, Dobbs R; EXE-T1D Consortium; Ellard S, Flanagan SE, Hattersley AT, Oram RA