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October 1, 2020 | Aliment Pharmacol Ther.
Hagopian Lab

A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care

Sharp SA, Jones SE, Kimmitt RA, Weedon MN, Halpin AM, Wood AR, Beaumont RN, King S, van Heel DA, Campbell PM, Hagopian WA, Turner JM, Oram RA.

October 1, 2020 | Diabetologia.
Hagopian Lab

The clinical consequences of heterogeneity within and between different diabetes types

Redondo MJ, Hagopian WA, Oram R, Steck AK, Vehik K, Weedon M, Balasubramanyam A, Dabelea D.

September 1, 2020 | Diabetes Care.
Hagopian Lab

Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study

Vehik K, Bonifacio E, Lernmark Å, Yu L, Williams A, Schatz D, Rewers M, She JX, Toppari J, Hagopian W, Akolkar B, Ziegler AG, Krischer JP; TEDDY Study Group

August 7, 2020 | Nat Med.
Hagopian Lab

A combined risk score enhances prediction of type 1 diabetes among susceptible children

Lauric A Ferrat, Kendra Vehik, Seth A Sharp, Åke Lernmark, Marian J Rewers, Jin-Xiong She, Anette-G Ziegler, Jorma Toppari, Beena Akolkar, Jeffrey P Krischer, Michael N Weedon, Richard A Oram, William A Hagopian; TEDDY Study Group

August 1, 2020 | Gut.
Hagopian Lab

Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study

Lindfors K, Lin J, Lee HS, Hyöty H, Nykter M, Kurppa K, Liu E, Koletzko S, Rewers M, Hagopian W, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Petrosino JF, Lloyd RE, Agardh D; TEDDY Study Group

August 1, 2020 | Diabetes.
Hagopian Lab

Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

Shapiro MR, Wasserfall CH, McGrail SM, Posgai AL, Bacher R, Muir A, Haller MJ, Schatz DA, Wesley JD, von Herrath M, Hagopian WA, Speake C, Atkinson MA, Brusko TM.

March 1, 2020 | Diabetes Care.
Hagopian Lab

Distinct Growth Phases in Early Life Associated With the Risk of Type 1 Diabetes: The TEDDY Study

Liu X, Vehik K, Huang Y, Elding Larsson H, Toppari J, Ziegler AG, She JX, Rewers M, Hagopian WA, Akolkar B, Krischer JP; TEDDY Study Group.

March 1, 2020 | Diabetes.
Hagopian Lab

Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study

Li Q, Parikh H, Butterworth MD, Lernmark Å, Hagopian W, Rewers M, She JX, Toppari J, Ziegler AG, Akolkar B, Fiehn O, Fan S, Krischer JP; TEDDY Study Group

February 1, 2020 | Diabetologia.
Hagopian Lab

Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study

Mattila M, Erlund I, Lee HS, Niinistö S, Uusitalo U, Andrén Aronsson C, Hummel S, Parikh H, Rich SS, Hagopian W, Toppari J, Lernmark Å, Ziegler AG, Rewers M, Krischer JP, Norris JM, Virtanen SM; TEDDY Study Group

December 2, 2019 | Nat Med.
Hagopian Lab

Prospective virome analyses in young children at increased genetic risk for type 1 diabetes

Kendra Vehik, Kristian F Lynch, Matthew C Wong, Xiangjun Tian, Matthew C Ross, Richard A Gibbs, Nadim J Ajami, Joseph F Petrosino, Marian Rewers, Jorma Toppari, Anette G Ziegler, Jin-Xiong She, Ake Lernmark, Beena Akolkar, William A Hagopian, Desmond A Schatz, Jeffrey P Krischer, Heikki Hyöty, Richard E Lloyd; TEDDY Study Group